Aureobasidin A

SKU: orb1298229

Description

Aureobasidin A is a cyclic peptide antifungal antibiotic that functions as a potent and specific inhibitor of inositolphosphorylceramide synthase (AUR1). It is widely used in biochemical research to study sphingolipid metabolism and has demonstrated antifungal activity in both in vitro and in vivo experimental models.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 127785-64-2
• MW: 1101.42
• Purity: 99.79%
• Formula: C₆₀H₉₂N₈O₁₁
• SMILES: [H][C@@]12CCCN1C(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C(C)C)N(C)C(=O)[C@]([H])(OC(=O)[C@@H](N(C)C(=O)[C@H](CC(C)C)NC(=O)[C@H](C(C)C)N(C)C(=O)[C@@]([H])(NC2=O)[C@H](C)CC)C(C)(C)O)[C@H](C)CC
• Target: Antibiotic,Parasite,Antifungal
• Solubility: DMSO:245 mg/mL (222.44 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (1.82 mM)

Bioactivity

• In Vitro:
  Ureobasidin A is a cyclicdepsipeptide antifungal produced by Aureobasidium pullulans with a strong fungicidal activity against a variety of fungi, including Candida.

Storage & Handling

• Storage: keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ceramide, Basifungin, Aureobasidin A, AUR1, Inhibitor, inositolphosphorylceramides, Fungal, inhibit, intoxication

Compound Identifiers

PubChem CID

9919816