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B355252

SKU: orb1218976

Description

B355252 protects against cell death caused by glutamate-evoked oxidative stress. B355252 shows neuroprotective effect, potentiating nerve growth factor (NGF)-induced neurite outgrowth.

Images & Validation

Key Properties

CAS Number1261576-81-1
MW514.06
Purity>98% (HPLC)
FormulaC25H24ClN3O3S2
SMILESC1CN(CCN1)C2=CC(=CC=C2)OC3=C(C=C(S3)S(=O)(=O)NCC4=CC=CC5=CC=CC=C54)Cl
TargetOthers
SolubilityDMSO:10 mM

Bioactivity

In Vivo
B-355252 (0.125 mg/kg; ip; daily; 3 days) significantly attenuates the infarct volume and protects post-stroke neuronal loss in adult male Sprague–Dawley rats with cerebral ischemia.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • B355252 [orb1298567]

    98.73%

    1261576-81-1

    514.06

    C25H24ClN3O3S2

    5 mg, 10 mg, 25 mg, 1 mg, 1 ml x 10 mM (in DMSO)
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Protocol Information

B355252 (orb1218976)

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% DMSO +
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Available Sizes

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100 mg
200 mg
500 mg
5 mg
$ 460.00
10 mg
$ 770.00
25 mg
$ 1,220.00
50 mg
$ 1,650.00