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AZD3229

SKU: orb1225604

Description

AZD3229 (AZD-3229) is a potent, pan-KIT mutant inhibitor with potent single digit nM growth inhibition against a diverse panel of mutant KIT driven Ba/F3 cell lines (GI50=1-50 nM); shows good margin to KDR-driven effects, also inhibits PDGFR mutants (Tel-PDGFRα, Tel-PDGFRβ, V561D/D842V).

Images & Validation

Key Properties

CAS Number2248003-60-1
MW479.516
Purity>98% (HPLC)
FormulaC24H26FN7O3
SMILESO=C(NC1=CC=C(NC2=C3C(F)=CC(OCCOC)=CC3=NC=N2)C=C1)CN4N=NC(C(C)C)=C4
Targetc-Kit
SolubilityDMSO: 95 mg/mL (198.12 mM); Water: Insoluble ( < 1 mg/ml refers to the product slightly soluble or insoluble )

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

AZD-3229 | AZD 3229

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AZD3229 (orb1225604)

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Available Sizes

Select a size below

200 mg
500 mg
5 mg
$ 250.00
10 mg
$ 390.00
25 mg
$ 680.00
50 mg
$ 990.00
100 mg
$ 1,380.00