Avicularin

SKU: orb1300263

Description

Avicularin is a bioactive flavonoid with demonstrated anti-allergic, anti-inflammatory, and hepatoprotective properties. Its research applications include studying anti-tumor mechanisms in hepatocellular carcinoma models via NF-κB/COX-2/PPAR-γ modulation and investigating anti-inflammatory pathways in LPS-stimulated macrophages through ERK inhibition.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Molecular Biology, Neuroscience, Signal Transduction

Key Properties

• CAS Number: 572-30-5
• MW: 434.35
• Purity: 99.94%
• Formula: C₂₀H₁₈O₁₁
• SMILES: OC[C@@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)-c2ccc(O)c(O)c2)[C@H](O)[C@H]1O
• Target: transporter,NF-κB,Apoptosis,ERK,PPAR,COX
• Solubility: DMSO:Soluble;H2O:1.15 mg/mL (2.65 mM)

Storage & Handling

• Storage: store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

COX, Cyclooxygenase, 3T3-L1, Alzheimer's disease, adipocytes, Apoptosis, Avicularin, GLUT, Glucose transporter, ECM, Extracellular signal regulated kinases, ERK, Fenicularin, HCC, Inhibitor, inhibit, inflammation, lipids, LPS, macrophages, Nuclear factor-κB, Nuclear factor-kappaB, NF-κB, Peroxisome proliferator-activated receptors, PPAR, oxidative stress, osteoarthritis, RAW 264.7

Compound Identifiers

PubChem CID

5490064