Aurora kinase inhibitor-2

SKU: orb1298421

Description

Aurora kinase inhibitor-2

Research Area

Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 331770-21-9
• MW: 400.43
• Purity: 98.66% (May vary between batches)
• Formula: C₂₃H₂₀N₄O₃
• SMILES: COc1cc2ncnc(Nc3ccc(NC(=O)c4ccccc4)cc3)c2cc1OC
• Target: Aurora Kinase
• Solubility: DMSO:22.5 mg/mL (56.19 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.99 mM)

Bioactivity

• Target IC50:
  Aurora A:0.39 M|Aurora B:240 nM
• In Vitro:
  In MCF-7 cells, it blocks proliferation with an IC50 value of 1.25 M.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ATP-competitive, AuroraKinase, Aurora Kinase, Aurora-B, Aurora-A, Aurora kinase inhibitor 2, Aurora Kinase Inhibitor II, Aurora kinase inhibitor2, Aurora kinase inhibitor-2, Aurora A, IUN 70219, IUN70219, IUN-70219, inhibit, Inhibitor

Compound Identifiers

PubChem CID

6610278