Aurora B Antibody / AURKB

• Catalog Number: orb534225
• Category: Antibodies
• Description: Aurora B is a serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. [UniProt]
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: ARRK2-1
• Tested applications: IHC-P
• Reactivity: Human
• Isotype: Mouse IgG1
• Immunogen: Amino acids 89-251 were used as the immunogen for this AURKB antibody.
• Dilution range: IHC (FFPE): 1-2ug/ml for 30 min at RT
• Purity: Protein G affinity
• Conjugation: Unconjugated
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
• Hazard Information: This AURKB antibody is available for research use only.
• UniProt ID: Q96GD4
• Storage: Store the AURKB antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
• Buffer/Preservatives: 0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced) and 0.05% sodium azide
• Note: For research use only
• Application notes: Optimal dilution of the AURKB antibody should be determined by the researcher.
• Expiration Date: 12 months from date of receipt.