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AT-007

SKU: orb1218435

Description

AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM). It reduces toxic galactitol levels and prevents disease complications in GALT deficiency rats.

Images & Validation

Key Properties

CAS Number2170729-29-8
MW425.4
Purity>98% (HPLC)
FormulaC17H10F3N3O3S2
SMILESOC(CC(c1cscc11)=NN(Cc2nc(cc(C(F)(F)F)cc3)c3s2)C1=O)=O
TargetReductase
SolubilityDMSO:35.71 mg/mL (83.94 mM; Need ultrasonic)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • AT-007 [orb1309970]

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    2170729-29-8

    425.4

    C17H10F3N3O3S2

    5 mg, 25 mg, 1 ml x 10 mM (in DMSO), 50 mg, 100 mg, 1 mg, 10 mg
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AT-007 (orb1218435)

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Available Sizes

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200 mg
500 mg
5 mg
$ 230.00
10 mg
$ 350.00
25 mg
$ 620.00
50 mg
$ 900.00
100 mg
$ 1,270.00