Amoxicillin

SKU: orb1310072

Description

Amoxicillin

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 26787-78-0
• MW: 365.4
• Purity: 99.92%
• Formula: C₁₆H₁₉N₃O₅S
• SMILES: [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)c1ccc(O)cc1)C(O)=O
• Target: Antibiotic,Antibacterial
• Solubility: Ethanol:< 1 mg/mL (insoluble or slightly soluble);DMSO:250 mg/mL (684.18 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.47 mM)

Bioactivity

• In Vivo:
  Amoxicillin was released more rapidly from phosphate buffer solution at pH 7.8 than from hydrochloric acid at pH 1.0. Amoxicillin was degraded in hydrochloric acid solution at 37℃, pH 1.0, indicating that Amoxicillin is less stable in acidic envir nMent.Amoxicillin (≤8 mg/ml) inhibited 4 out of 15 strains.Amoxicillin (4 mg/ml) in combination with clavulanic acid (≤2 mg/ml) Amoxicillin (4 mg/ml) in combination with clavulanic acid (≤2 mg/ml) inhibited 14 out of 15 strains. In combination with cefotaxime (4 mg/ml) the IC50 of Amoxicillin o the strains was reduced from 0.5 mg mL to 0.06 mg/ml, ranging from 0.01 to 0.25 mg/mL.Amoxicillin-treated cells secreted large amounts of IL-5, with little or no secretion of IL-4, TNFα, and interferon-gamma. Amoxicillin-specific T-cell clones did not exhibit drug-specific cytotoxicity, but were present to kill target cells at concanavalin A, suggesting that its Primary capacity is cytolysis.

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

cell wall, Bacterial, antimicrobial, antibiotic, Antibiotic, Amoxycillin, Amoxicillin, Inhibitor, inhibit, polypeptides

Compound Identifiers

PubChem CID

33613