β-Amanitin

SKU: orb1989700

Description

β-Amanitin is a potent cyclic peptide toxin from the death cap mushroom that selectively inhibits eukaryotic RNA polymerases II and III. It is widely used in molecular biology research to study transcription mechanisms, regulate gene expression in vitro, and has been employed in vivo to model hepatotoxicity.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 21150-22-1
• MW: 919.96
• Formula: C₃₉H₅₃N₉O₁₅S
• SMILES: [H][C@@]12C[C@@H](O)CN1C(=O)[C@]([H])(CC(O)=O)NC(=O)[C@]1([H])C[S@](=O)c3[nH]c4cc(O)ccc4c3C[C@]([H])(NC(=O)[C@@]([H])(NC2=O)[C@@H](C)[C@@H](O)CO)C(=O)NCC(=O)N[C@@]([H])([C@@H](C)CC)C(=O)NCC(=O)N1
• Target: ADC Cytotoxin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

125181298