γ-Amanitin

SKU: orb1691220

Description

γ-Amanitin is a mushroom-derived cytotoxin used in ADC development. It potently inhibits RNA polymerase II, halting mRNA synthesis, similar to α- and β-Amanitin. This mechanism is utilized in research for studying transcription and evaluating targeted cancer therapies in vitro and in vivo.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 21150-23-2
• MW: 902.98
• Formula: C₃₉H₅₄N₁₀O₁₃S
• SMILES: CCC(C)C1NC(=O)CNC(=O)C2Cc3c([nH]c4cc(O)ccc34)S(=O)CC(NC(=O)CNC1=O)C(=O)NC(CC(N)=O)C(=O)N1CC(O)CC1C(=O)NC(C(C)C(C)O)C(=O)N2
• Target: ADC Cytotoxin,DNA/RNA Synthesis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

107839