Ala-Ala-Asn-PAB

SKU: orb1988819

Description

Ala-Ala-Asn-PAB is a protease-cleavable linker used in ADC development to enhance drug stability and reduce off-target toxicity. It enables controlled payload release in tumor cells and is widely applied in both in vitro cytotoxicity assays and in vivo xenograft studies for targeted cancer therapy research.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2149584-00-7
• MW: 379.41
• Purity: 97.31% (May vary between batches)
• Formula: C₁₇H₂₅N₅O₅
• SMILES: [C@H](C(NC1=CC=C(CO)C=C1)=O)(NC([C@@H](NC([C@H](C)N)=O)C)=O)CC(N)=O
• Target: PROTAC Linker,Others,ADC Linker

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Ala-Ala-Asn-PAB

Compound Identifiers

PubChem CID

118966102