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Azido-PEG5-Ala-Ala-Asn-PAB

SKU: orb1989485

Description

This cleavable linker, featuring a 5-unit PEG spacer and a para-aminobenzylcarbamate (PAB) self-immolative moiety, is designed for constructing antibody-drug conjugates (ADCs). It is utilized in both in vitro and in vivo research to develop targeted cancer therapies, enabling controlled drug release at tumor sites.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2055048-54-7
MW696.759
FormulaC30H48N8O11
SMILESC[C@H](NC(=O)CCOCCOCCOCCOCCOCCN=[N+]=[N-])C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)Nc1ccc(CO)cc1
TargetPROTAC Linker,ADC Linker

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

Azido-PEG5-Ala-Ala-Asn-PAB (orb1989485)

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