AkaLumine

SKU: orb1698610

Description

AkaLumine

Key Properties

• CAS Number: 1176235-08-7
• MW: 302.39
• Purity: 97.17%
• Formula: C₁₆H₁₈N₂O₂S
• SMILES: C(=C/C=C/C1=CC=C(N(C)C)C=C1)\C2=N[C@@H](C(O)=O)CS2

Bioactivity

• In Vivo:
  In a time course of bioluminescence production in vivo, AkaLumine displayed a stable glow-type reaction at various injection doses and its bioluminescence production remained elevated longer at the higher concentrations; this temporally more stable bioluminescence production may be beneficial for acquiring images without influence of acquisition time. Furthermore, AkaLumine has a relatively longer half-life (∼40 min) in serum. These results suggest that AkaLumine would be a suitable substrate for in vivo imaging.
• In Vitro:
  In LLC/luc and MDA-MB-231/Luc cells treated with AkaLumine, the signal began to peak at a lower concentration of 2.5 μM. In contrast, bioluminescence produced by D-luciferin and CycLuc1 continued to rise with increasing concentration and did not reach a significant saturation point even at the highest concentration of 250 μM.

Storage & Handling

• Storage: keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Aka Lumine, AkaLumine

Compound Identifiers

PubChem CID

58133337