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AGO1 (N1) Antibody, Rabbit Polyclonal

Catalog Number: orb67054

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$ 440.00
Catalog Numberorb67054
CategoryAntibodies
DescriptionRabbit polyclonal to AGO1.Argonaute1 (AGO1) is also known as Eukaryotic translation initiation factor 2C 1 (EIF2C1), which is amember of the Argonaute family of proteins that play a role in RNA interference. AGO1 is highly basic,and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in shortinterfering-RNA-mediated gene silencing. AGO1 binds to short RNAs such as microRNAs (miRNAs)or short interfering RNAs (siRNAs), and represses the translation of mRNAs complementary to them.AGO1 lacks endonuclease activity and does not appear to cleave target mRNAs. AGO1 is alsorequired for transcriptional gene silencing (TGS) of promoter regions which are complementary tobound short antigene RNAs
ClonalityPolyclonal
Species/HostRabbit
ConjugationUnconjugated
ReactivityHuman
Buffer/Preservatives0.01% NaN3
PurityAffinity purification
ImmunogenN-terminal region of human AGO1
UniProt IDQ9UL18
MW97
Tested applicationsWB
Dilution rangeWB:1:1000-1:5000
Storage-20°C
Alternative namesanti-AGO1 antibody,anti-Protein argonaute1 antibod
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NoteFor research use only
Expiration Date12 months from date of receipt.
AGO1 (N1) Antibody, Rabbit Polyclonal

Western blot of total cell extracts from human K562 using AGO1 antibody