You have no items in your shopping cart.
You have no items in your shopping cart.
Catalog Number | orb67054 |
---|---|
Category | Antibodies |
Description | Rabbit polyclonal to AGO1.Argonaute1 (AGO1) is also known as Eukaryotic translation initiation factor 2C 1 (EIF2C1), which is amember of the Argonaute family of proteins that play a role in RNA interference. AGO1 is highly basic,and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in shortinterfering-RNA-mediated gene silencing. AGO1 binds to short RNAs such as microRNAs (miRNAs)or short interfering RNAs (siRNAs), and represses the translation of mRNAs complementary to them.AGO1 lacks endonuclease activity and does not appear to cleave target mRNAs. AGO1 is alsorequired for transcriptional gene silencing (TGS) of promoter regions which are complementary tobound short antigene RNAs |
Clonality | Polyclonal |
Species/Host | Rabbit |
Conjugation | Unconjugated |
Reactivity | Human |
Buffer/Preservatives | 0.01% NaN3 |
Purity | Affinity purification |
Immunogen | N-terminal region of human AGO1 |
UniProt ID | Q9UL18 |
MW | 97 |
Tested applications | WB |
Dilution range | WB:1:1000-1:5000 |
Storage | -20°C |
Alternative names | anti-AGO1 antibody,anti-Protein argonaute1 antibod Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Western blot of total cell extracts from human K562 using AGO1 antibody