AGO1 (N1) Antibody, Rabbit Polyclonal

SKU: orb67054

Description

Rabbit polyclonal to AGO1.Argonaute1 (AGO1) is also known as Eukaryotic translation initiation factor 2C 1 (EIF2C1), which is amember of the Argonaute family of proteins that play a role in RNA interference. AGO1 is highly basic,and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in shortinterfering-RNA-mediated gene silencing. AGO1 binds to short RNAs such as microRNAs (miRNAs)or short interfering RNAs (siRNAs), and represses the translation of mRNAs complementary to them.AGO1 lacks endonuclease activity and does not appear to cleave target mRNAs. AGO1 is alsorequired for transcriptional gene silencing (TGS) of promoter regions which are complementary tobound short antigene RNAs

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:1000-1:5000
• Reactivity: Human

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: N-terminal region of human AGO1
• Molecular Weight: 97
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-AGO1 antibody,anti-Protein argonaute1 antibody,anti-Argonaute1 antibody,anti-hAgo1 antibody,anti-Eukaryotic translation initiation factor 2C 1 antibody,anti-eIF2C 1 antibody,anti-eIF2C 1 antibody,anti-Putative RNAbinding protein Q99 antibody

Western blot of total cell extracts from human K562 using AGO1 antibody

Quick Database Links

UniProt

Q9UL18