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AGB1

SKU: orb3132660

Description

AGB1 is a highly selective and potent B&H-PROTAC degrader. It degrades Ab:Brd4BD2 L387A and Ab:BromoTag-Brd2 with pDC50 values of 7.8 and 7.9, respectively. AGB1 has an affinity for VHL with a Kd of 125 nM. In mice, AGB1 exhibits favorable pharmacokinetic properties [DC50, 6 h approximately 13 nM].

Images & Validation

Key Properties

FormulaC51H63ClN8O9S2
TargetPROTACs,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

AGB1 (orb3132660)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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