Afatinib (Standard)

SKU: orb3141335

Description

Afatinib (Standard) is a reference standard for research and analysis in studies involving Afatinib. Afatinib (BIBW 2992) is an EGFR family inhibitor that inhibits EGFRwt, EGFRL858R, EGFRL858R/T790M, and HER2 (IC50=0.5/0.4/10/14 nM) with irreversible and oral activity. Afatinib has antitumor activity.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 850140-72-6
• MW: 485.94
• Formula: C₂₄H₂₅ClFN₅O₃
• SMILES: N(C=1C2=C(C=C(O[C@H]3CCOC3)C(NC(/C=C/CN(C)C)=O)=C2)N=CN1)C4=CC(Cl)=C(F)C=C4
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Others