Afatinib D6

SKU: orb1992960

Description

Afatinib D6 (BIBW 2992 D6) is a deuterated analog of the irreversible EGFR family inhibitor Afatinib. This labeled compound is used as an internal standard in quantitative LC-MS analysis for pharmacokinetic and metabolic studies in both in vitro and in vivo cancer research.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 1313874-96-2
• MW: 491.98
• Formula: C₂₄H₂₅ClFN₅O₃
• SMILES: N(C=1C2=C(C=C(O[C@H]3CCOC3)C(NC(/C=C/CN(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)=C2)N=CN1)C4=CC(Cl)=C(F)C=C4
• Target: EGFR,Autophagy

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

53254174