ADHP

SKU: orb1307232

Description

ADHP

Key Properties

• CAS Number: 119171-73-2
• MW: 257.24
• Purity: 99.57%
• Formula: C₁₄H₁₁NO₄
• SMILES: OC1=CC=C2C(OC(C=C(O)C=C3)=C3N2C(C)=O)=C1
• Target: Others
• Solubility: DMSO:60 mg/mL (233.25 mM)

Bioactivity

• In Vitro:
  To obtain the parameters Km and kcat for Compound I, two independent methods are used. Initially, the oxidation of ADHP using the injector functionality built-in to the fluorescence plate reader is studied. The auto-injector dispenses the H2O2 to initiate the reaction, as a means of generating a set of progress curves. Analysis for MPO-mediated oxidation of ADHP gives a Km of 31±4 μM and the kcat of 186± 6/s. The kobs also increase over the experimental range of ADHP concentrations from 1 to 80 μM and for the converse experiment holding substrate constant over 3 to 45 nM MPO. The apparent second-order rate constant obtain from the slope of kobs against ADHP concentration Kappon is 2.1±0.2 mM/s.

Storage & Handling

• Storage: store at low temperature,store under nitrogen,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, 10-Acetyl-3,7-dihydroxyphenoxazine, ADHP

Compound Identifiers

PubChem CID

167453