Ac-CoA Synthase Inhibitor1

SKU: orb1302904

Description

Ac-CoA Synthase Inhibitor1

Research Area

Infectious Disease & Virology, Metabolism Research

Key Properties

• CAS Number: 508186-14-9
• MW: 410.51
• Purity: 99.84%
• Formula: C₂₀H₁₈N₄O₂S₂
• SMILES: COCCNC(=O)Nc1ccc2nc(-c3cccs3)c(nc2c1)-c1cccs1
• Target: Fatty Acid Synthase,RSV
• Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:40 mg/mL (97.44 mM);Ethanol:2 mg/mL (4.87 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.87 mM)

Bioactivity

• Target IC50:
  ACSS2:0.6 μM
• In Vitro:
  This quinoxaline compound inhibits the ability of HepG2 cells to incorporate [14C]acetate into lipids with IC50 = 6.8 μM. The quinoxaline is also able to inhibit HepG2 utilization of [14C]acetate for histone acetylation with IC50 = 5.5 μM.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Fatty Acid Synthase, FattyAcidSynthase, Inhibitor, inhibit, acetate-dependent, ACSS2, ACSS2 inhibitor, acetyl-CoA, Ac CoA Synthase Inhibitor1, AcCoA Synthase Inhibitor1, Ac-CoA Synthase Inhibitor1, Ac-CoA Synthase Inhibitor-1, synthetase, syncytial, RSV, Respiratory syncytial virus, respiratory, virus

Compound Identifiers

PubChem CID

2300455