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A-740003
Catalog Number: orb1303893
| Catalog Number | orb1303893 |
|---|---|
| Category | Small Molecules |
| Description | A-740003 |
| CAS Number | 861393-28-4 |
| Purity | 99.51% |
| MW | 474.55 |
| SMILES | N(=C(NC(NC(CC1=CC(OC)=C(OC)C=C1)=O)C(C)(C)C)NC#N)C=2C3=C(C=CC2)N=CC=C3 |
| Formula | C26H30N6O3 |
| Biological Activity | A-740003 (A 740003) is an effective and specific P2X7 receptor antagonist (IC50: 18/40 nM, for rat/human). It can reduce nociception in animal models of persistent neuropathic and inflammatory pain, and also reduce neuroblastoma tumor growth in mice. |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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