A-740003

• Catalog Number: orb1303893
• Category: Small Molecules
• Description: A-740003
• CAS Number: 861393-28-4
• Purity: 99.51%
• MW: 474.55
• SMILES: COc1ccc(CC(=O)NC(N\C(Nc2cccc3ncccc23)=N\C#N)C(C)(C)C)cc1OC
• Formula: C₂₆H₃₀N₆O₃
• Biological Activity: A-740003 (A 740003) is an effective and specific P2X7 receptor antagonist (IC50: 18/40 nM, for rat/human). It can reduce nociception in animal models of persistent neuropathic and inflammatory pain, and also reduce neuroblastoma tumor growth in mice.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.