ZLD1039

• Catalog Number: orb1698904
• Category: Small Molecules
• Description: ZLD1039
• CAS Number: 1826865-46-6
• Purity: 99.82%
• MW: 612.8
• SMILES: N(CC)(C1=CC(=CC(C(NCC2=C3C(=C(C)NC2=O)CCCC3)=O)=C1C)C=4C=CC(=NC4)N5CCN(C)CC5)C6CCOCC6
• Formula: C₃₆H₄₈N₆O₃
• Biological Activity: ZLD1039 is a potent, orally bioavailable EZH2 (Enhancer of Zeste Homolog 2) inhibitor with high selectivity. It demonstrates strong, concentration-dependent inhibition of both wild-type and mutant (Y641F and A677G) PRC2 (Polycomb Repressive Complex 2) enzymatic activities, exhibiting IC50 values of 5.6, 15, and 4.0 nM, respectively. Additionally, ZLD1039 effectively suppresses breast tumor growth and metastasis.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.