ZJ 43

SKU: orb3027363

Description

ZJ43 is a potent inhibitor of glutamate carboxypeptidase II (K(i) = 0.8 nM) and III (K(i) = 23 nM) that inhibits the hydrolysis of NAAG (IC50 = 2.4 nM). ZJ43 sufficiently activates group II mGluR and reduces some of the behavioral effects of PCP. ZJ43 shows an analgesic effect in neuropathic and inflammatory and pain models.

Research Area

Metabolism Research, Neuroscience

Key Properties

• CAS Number: 723331-20-2
• MW: 607.59
• Formula: C₂₄H₃₉N₄O₁₄
• SMILES: CC(C)C[C@H](NC(N[C@@H](CCC(O)=O)C(O)=O)=[O]CC(C)C[C@H](NC(=O)N[C@@H](CCC(O)=O)C(O)=O)C(O)=O)C(O)=O
• Target: GluR,Aminopeptidase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

GluR,Aminopeptidase