Z-VAE(OMe)-fmk

SKU: orb1737894

Description

Z-VAE(OMe)-fmk is a cell-permeable, irreversible inhibitor of UCHL1 that uniquely binds to the enzyme's P1' site, mimicking the proposed binding mode of an endogenous substrate's C-terminal extension. This compound is a valuable chemical tool for probing UCHL1 function in neurodegenerative disease models and ubiquitin-proteasome system research both in vitro and in vivo.

Key Properties

• Target: Others
• CAS Number: 1027141-02-1
• MW: 481.51
• Formula: C₂₃H₃₂FN₃O₇
• SMILES: [C@H](NC([C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)[C@@H](C)C)=O)C)=O)(CCC(OC)=O)C(CF)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

5497177