(Z)-Semaxinib

• Catalog Number: orb1305395
• Category: Small Molecules
• Description: (Z)-Semaxinib
• Purity: 99.94%
• MW: 238.28
• Biological Activity: (Z)-Semaxinib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR over PDGFRβ, no inhibition for FGFR, InsR, and EGFR. (Z)-Semaxinib is a quinolone derivative with potential antineoplastic activity.
• CAS Number: [194413-58-6]
• Formula: C₁₅H₁₄N₂O
• SMILES: C(=C\1/C=2C(NC1=O)=CC=CC2)\C=3NC(C)=CC3C
• Storage: -20°C
• Note: For research use only