YW2065

SKU: orb3177763

Description

YW2065 has excellent anti-colorectal cancer effects in vitro and in vivo. YW2065 achieves its inhibitory activity for Wnt signaling by stabilizing Axin-1, a scaffolding protein that regulates proteasome degradation of β-catenin. Simultaneously, YW2065 also led to the activation of the tumor suppressor AMPK, providing an additional anticancer mechanism. In addition, YW2065 showed favorable pharmacokinetic properties without obvious toxicity.

Key Properties

• CAS Number: 2131223-85-1
• MW: 407.26
• Formula: C₂₀H₁₅BrN₄O
• SMILES: CC=1N(N=CC1C(NC2=NC3=C(C=C2)C=CC=C3)=O)C4=C(Br)C=CC=C4
• Target: Wnt/beta-catenin,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Wnt/beta-catenin,Others