YS-363

SKU: orb1944015

Description

YS-363 is a potent, selective, and orally bioavailable EGFR inhibitor with IC50 values of 0.96 nM (wild-type) and 0.67 nM (L858R mutant). It induces G0/G1 cell cycle arrest and apoptosis in vitro and has demonstrated antitumor efficacy in vivo, making it a valuable tool for oncology research targeting EGFR-driven cancers.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2470908-90-6
• MW: 494.58
• Formula: C₃₀H₃₀N₄O₃
• SMILES: N=1C=NC(=C2C=C(OCCCN3CCOCC3)C(OC)=CC12)C=4C=5C=CC=CC5NC4C=6C=CC=CC6
• Target: EGFR,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

164615696