Yohimbine hydrochloride

SKU: orb1306369

Description

Yohimbine HCl is a plant alkaloid and selective α2-adrenergic receptor antagonist that increases norepinephrine and dopamine release. It is widely used in research for studying erectile dysfunction, mydriasis, and for establishing experimental hypertension models in both in vitro and in vivo studies.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 65-19-0
• MW: 390.90
• Purity: >99.99% (May vary between batches)
• Formula: C₂₁H₂₇ClN₂O₃
• SMILES: COC(=O)[C@H]1[C@H](CC[C@@H]2[C@@H]1C[C@H]3C4=C(CCN3C2)C5=CC=CC=C5N4)O.Cl
• Target: Adrenergic Receptor
• Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble);Ethanol:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.12 mM);DMSO:42.5 mg/mL (108.72 mM)

Bioactivity

• In Vivo:
  LD50: 55 mg/kg,i.p.,mice

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AdrenergicReceptor, Adrenergic Receptor, Antagonil, Beta Receptor, inhibit, Inhibitor, Yohimbine HCl, Yohimbine hydrochloride, Yohimbine Hydrochloride, Yohimbine, α2 adrenergic receptor

Compound Identifiers

PubChem CID

6169