yGsy2p-IN-1

SKU: orb1298699

Description

yGsy2p-IN-H23 is a pyrazole-based small molecule inhibitor targeting yeast glycogen synthase 2 (yGsy2p) and human glycogen synthase 1 (hGYS1). It serves as a valuable research tool for investigating glycogen metabolism and has been utilized in in vitro studies relevant to glycogen storage diseases (GSDs).

Key Properties

• CAS Number: 2415003-97-1
• MW: 352.26
• Purity: 99.67% (May vary between batches)
• Formula: C₁₆H₁₁F₃N₂O₄
• SMILES: Oc1ccc(cc1)-c1c(n[nH]c1C(F)(F)F)-c1ccc(O)c(O)c1O
• Target: Others
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.68 mM);DMSO:62.5 mg/mL (177.43 mM)

Bioactivity

• Target IC50:
  GYS1 (WT, human):1.31 µM (Ki)|GYS1 (human):2.75 µM (IC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

synthase, storage, yGsy2p, yGsy2p IN 1, yGsy2pIN1, yGsy-2p-IN-1, yGsy2p-IN-1, yeast, pyrazole, inhibit, human, GSDs, glycogen, Inhibitor, hGYS1, Hgys1, diseases

Compound Identifiers

PubChem CID

146673157