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XT2

SKU: orb1688437

Description

XT2 is a potent and selective oral NIK inhibitor (IC50 = 9.1 nM). It demonstrates efficacy in acute liver injury models by reducing ALT levels and immune cell infiltration, highlighting its utility for research in liver inflammation and NF-κB pathway biology.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number2582816-37-1
MW379.41
FormulaC19H14FN5OS
SMILESC[C@@](O)(C#Cc1ccc(F)c(c1)-c1c[nH]c2cnc(N)nc12)c1nccs1
TargetNF-κB,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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XT2 (orb1688437)

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