WST-8

SKU: orb1303299

Description

WST-8

Key Properties

• CAS Number: 193149-74-5
• MW: 600.47
• Purity: 99.94%
• Formula: C₂₀H₁₃N₆NaO₁₁S₂
• SMILES: [Na+].COc1cc(ccc1-[n+]1nc(nn1-c1ccc(cc1)[N+]([O-])=O)-c1ccc(cc1S([O-])(=O)=O)S([O-])(=O)=O)[N+]([O-])=O
• Target: Others
• Solubility: 10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (1.67 mM);H2O:50 mg/mL (83.27 mM);DMSO:255 mg/mL (424.67 mM)

Bioactivity

• In Vitro:
  METHODS: A commonly used MTS-based assay was compared to a bioassay using the water-soluble tetrazolium dye WST-8 at a concentration of 7 × 10(5) cells/ml with 800 IU/ml PEGylated G-CSF at 24, 48, 72, and 72 h time points to determine the efficacy of PEGylated G-CSF. In addition, the optimized WST-8 dye-based assay was used to test the potency of various commercially available PEGylated G-CSF formulations. RESULTS The results demonstrated that the WST-8-based assay had greater sensitivity in determining the potency of PEGylated G-CSF using the NFS-60 cell line compared to the conventional MTS-based assay.

Storage & Handling

• Storage: keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, WST8, WST-8, WST 8

Compound Identifiers

PubChem CID

9894947