WRN (N) Antibody, Rabbit Polyclonal

SKU: orb66915

Description

Rabbit polyclonal to WRN.WRN (Werner syndrome ATP-dependent helicase) is a magnesium and ATP-dependent DNAhelicase.WRN also has the 3 to 5 exonuclease activity towards double-stranded DNA with 5-overhang, but not single-stranded DNA or blunt-ended double stranded DNA. WRN plays animportant role in the dissociation of joint DNA molecules and the formation of DNA replication focalcenters. Defects in WRN causes Werner syndrome.

Research Area

Cancer, DNA Damage, Epigenetics

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:1000-1:5000
• Reactivity: Human

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: N-terminal region of human WRN
• Molecular Weight: 162
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-WRN antibody,anti-RECQ3 antibody,anti-RECQL2 antibody

Western blot analysis of total cell extracts from human Hela using WRN antibody

Quick Database Links

UniProt

Q14191