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WLB-89462

SKU: orb2277779

Description

WLB-89462 (Compound 20c) is a potent and selective σ2 receptor ligand (K i = 13 nM) demonstrating neuroprotective effects. It has been shown to rescue Aβ-induced memory deficits in rodent models and possesses a favorable pharmacokinetic profile with good brain penetration and oral bioavailability, supporting its use in neurodegenerative disease research.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2849471-75-4
MW399.49
FormulaC21H29N5O3
SMILESC(C)C=1N=C(C(=CN1)C2=CC(C)=NO2)C3CCN(CC(=O)N4CCOCC4)CC3
TargetSigma receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

WLB-89462 (orb2277779)

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