WIZ degrader 1

SKU: orb2646158

Description

Compound 141 is a potent, small molecule WIZ degrader (AC50 = 2 nM) that induces fetal hemoglobin (HbF) expression (EC50 = 6 mM). It serves as a valuable research tool for studying genetic blood disorders, such as sickle cell disease and beta-thalassemia, in both cellular and preclinical models.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 2839552-68-8
• MW: 473.56
• Formula: C₂₅H₃₃F₂N₅O₂
• SMILES: C(C1=CC2=C(C=NN2C=C1)N3C(=O)NC(=O)CC3)[C@H]4C[C@H](C)N(CC5CCC(F)(F)CC5)CC4
• Target: Others,Histone Methyltransferase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

165128461