VU0453595

SKU: orb1304850

Description

VU0453595 is a selective positive allosteric modulator (PAM) of the muscarinic M1 receptor. It is used in neuroscience research to investigate M1 receptor function in models of cognitive disorders, with applications in both in vitro and in vivo experimental systems.

Research Area

Neuroscience

Key Properties

• CAS Number: 1432436-13-9
• MW: 322.34
• Purity: 99.91% (May vary between batches)
• Formula: C₁₈H₁₅FN₄O
• SMILES: Cn1cc(cn1)-c1ccc(CN2Cc3ncccc3C2=O)c(F)c1
• Target: AChR
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (12.41 mM);DMSO:100 mg/mL (310.23 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

positive, schizophrenia, systemically, VU0453595, VU-0453595, VU 0453595, PAM, M1 mAChR, mAChR, modulator, inhibit, Muscarinic acetylcholine receptor, Inhibitor, allosteric

Compound Identifiers

PubChem CID

71555066