VU 0465350

SKU: orb692051

Description

VU 0465350 is a potent, specific BMP receptor activin receptor-like kinase 3 (ALK3) antaognist with Ki of 92.3 nM; shows no activity for ALK2/4/5, also shows affinity for TGFBR2, VEGFR2 and AMPK; blocks SMAD phosphorylation in vitro and in vivo, and enhances liver regeneration after partial hepatectomy.

Key Properties

• CAS Number: 1414843-61-0
• MW: 318.38
• Purity: >98%
• Formula: C₁₉H₁₈N₄O
• SMILES: C12=NC=C(C3=CNN=C3)N1C=CC(C1=CC=C(OC(C)C)C=C1)=C2

Storage & Handling

• Storage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

56593417