VRT-325

SKU: orb1694908

Description

VRT-325 is a corrector compound that addresses CFTR folding defects by facilitating NBD dimerization and TMD folding. It accelerates the repair of CFTR-mediated epithelial function in vitro, as demonstrated by its enhancement of wound healing rates in cystic fibrosis cell monolayer assays.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 815592-21-3
• MW: 510.65
• Purity: 99.58% (May vary between batches)
• Formula: C₂₇H₃₄N₄O₄S
• SMILES: O(C=1C2=C(N=C(C(C)N3CCN(S(=O)(=O)C4=CC=C(OC)C=C4)CC3)N1)C=CC=C2)C5CCCCC5
• Target: Others,CFTR
• Solubility: DMSO:45 mg/mL (88.12 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CF106951, CF-106951, CF 106951, CFcor 325, CFcor325, CFcor-325, VRT 325, VRT 534, VRT325, VRT-325, VRT534, VRT-534

Compound Identifiers

PubChem CID

11957831