VH 032 amide-PEG1-acid

SKU: orb1693874

Description

This functionalized VHL ligand is a key building block for PROTAC synthesis, featuring an E3 ligase binder connected via a PEG1 linker to a carboxylic acid for target warhead conjugation. It is widely used in both cellular and in vitro assays to develop degraders for cancer and disease-related proteins.

Research Area

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2172820-07-2
• MW: 574.69
• Formula: C₂₈H₃₈N₄O₇S
• SMILES: Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCC(O)=O)C(C)(C)C)cc1 |@:34|
• Target: DNA Alkylator/Crosslinker,E3 Ligase Ligand-Linker Conjugates,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

134184040