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Vc-seco-DUBA

SKU: orb1988014

Description

Vc-seco-DUBA is an antibody-drug conjugate (ADC) linker-payload conjugate, combining the DNA alkylating agent DUBA via a Vc-seco linker. It is a research tool for developing ADCs with potent antitumor activity, applicable in both in vitro cytotoxicity assays and in vivo xenograft model studies.

Research Area

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1345681-58-4
MW1331.81
FormulaC65H75ClN12O17
SMILESC(Cl)[C@H]1C2=C(N(C(=O)C=3N=C4N(C3)C=C(NC(=O)C5=CC=C(O)C=C5)C=C4)C1)C=C(OC(N(CCN(C(OCC6=CC=C(NC([C@@H](NC([C@@H](NC(OCCOCCN7C(=O)C=CC7=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C6)=O)C)CCOCCO)=O)C=8C2=C(C)C=CC8
TargetDNA Alkylation,Apoptosis,Drug-Linker Conjugates for ADC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information

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1 mg
$ 800.00
5 mg
$ 3,610.00
DispatchUsually dispatched within 5-10 working days
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