Valproic acid-d14 sodium

SKU: orb3139004

Description

Valproic acid-d14 (sodium) is the deuterated form of Valproic acid (sodium). Valproic acid sodium salt (Sodium Valproate) acts as an HDAC inhibitor, with an IC50 range of 0.5-2 mM, and inhibits the activity of HDAC1 (IC50, 400 μM) while also promoting the degradation of HDAC2. It activates the Notch1 signaling pathway and suppresses the proliferation of small cell lung cancer (SCLC) cells. Additionally, Valproic acid sodium salt is applicable in research related to epilepsy, bipolar disorder, and migraines.

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Key Properties

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Target	Autophagy,HDAC,HIV Protease,Gamma-secretase,Mitophagy,Endogenous Metabolite

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Autophagy,HDAC,HIV Protease,Gamma-secretase,Mitophagy,Endogenous Metabolite

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