Valbenazine

SKU: orb1227129

Description

A novel, highly selective vesicular monoamine transporter 2 (VMAT2) inhibitor; is approved for the treatment of tardive dyskinesia.Other Indication Phase 3 Clinical(In Vitro):Valbenazine exhibits VMAT2 binding affinity in rat striatum and human platelets with Kis of 110 and 150 nM, respectively.\n(In Vivo):Valbenazine (10 mg/kg; orally) induces ptosis (primarily an adrenergic response) and increases plasma prolactin primarily a dopaminergic response.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1025504-45-3
• MW: 418.5695
• Purity: >98% (HPLC)
• Formula: C₂₄H₃₈N₂O₄
• SMILES: CC(C)CC1CN2CCC3=CC(=C(C=C3C2CC1OC(=O)C(C(C)C)N)OC)OC
• Target: Other Targets
• Solubility: 10 mM in DMSO

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NBI-98854

Quick Database Links

Gene Symbol

Other Targets