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Valbenazine

SKU: orb1227129

Description

A novel, highly selective vesicular monoamine transporter 2 (VMAT2) inhibitor; is approved for the treatment of tardive dyskinesia.Other Indication Phase 3 Clinical(In Vitro):Valbenazine exhibits VMAT2 binding affinity in rat striatum and human platelets with Kis of 110 and 150 nM, respectively.\n(In Vivo):Valbenazine (10 mg/kg; orally) induces ptosis (primarily an adrenergic response) and increases plasma prolactin primarily a dopaminergic response.

Images & Validation

Key Properties

CAS Number1025504-45-3
MW418.5695
Purity>98% (HPLC)
FormulaC24H38N2O4
SMILESCC(C)CC1CN2CCC3=CC(=C(C=C3C2CC1OC(=O)C(C(C)C)N)OC)OC
TargetOther Targets
Solubility10 mM in DMSO

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

NBI-98854

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Valbenazine (orb1227129)

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200 mg
500 mg
2 mg
$ 120.00
5 mg
$ 210.00
10 mg
$ 280.00
25 mg
$ 600.00
50 mg
$ 860.00
100 mg
$ 1,210.00