USP30 inhibitor 18

SKU: orb1303933

Description

USP30 inhibitor 18 is a potent and selective deubiquitinase inhibitor with an IC50 of 0.02 µM against USP30. This compound promotes mitophagy and enhances protein ubiquitination, making it a useful research tool for studying mitochondrial quality control, Parkinson's disease models, and related pathways in cellular assays.

Research Area

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery, Protein Biochemistry

Key Properties

• CAS Number: 2242582-40-5
• MW: 497.58
• Purity: 99.03% (May vary between batches)
• Formula: C₂₆H₂₈FN₃O₄S
• SMILES: CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2ccccc2)NC(=O)c2ccc(F)cc2)cc1
• Target: DUB,Mitophagy
• Solubility: 10% DMSO+90% Corn Oil:3.3 mg/mL (6.63 mM);DMSO:120 mg/mL (241.17 mM)

Bioactivity

• Target IC50:
  USP30:0.02 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DUBs, Deubiquitinase, Inhibitor, Mitophagy, Parkin, inhibit, USP30 inhibitor 18, USP-30 inhibitor 18, USP30

Compound Identifiers

PubChem CID

142474792