Urotensin-II receptor antagonist-1

SKU: orb2944750

Description

Urotensin-II receptor antagonist-1 is a potent, selective human UT receptor antagonist (Ki=16 nM) with low oral bioavailability in rats. This research compound also exhibits off-target activity against CYP enzymes, κ opioid receptors, and cardiac sodium channels, making it a useful tool for in vitro pharmacological profiling and cardiovascular research.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1034708-07-0
• MW: 460.439
• Formula: C₂₅H₃₁Cl₂N₃O
• SMILES: C([C@H]1[C@H](CCCN1C(CN(C)C2=CC(Cl)=C(Cl)C=C2)=O)C3=CC=CC=C3)N4CCCC4
• Target: GPCR,Opioid Receptor,Sodium Channel,Cytochromes P450

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

25067046