UNC0638 hydrate

SKU: orb2695503

Description

UNC0638 hydrate selectively inhibits G9a and GLP histone methyltransferases with IC50 values of 15 nM and 19 nM, respectively. It is effective in inhibiting invasion and migration of TNBC cells in vitro. Additionally, UNC0638 hydrate acts as an inhibitor of EHMT1/2 and induces the expression of fetal hemoglobin (HbF) in cultures of human erythroid progenitor cells. Furthermore, it exhibits antiviral activity against FMDV (foot-and-mouth disease virus) and VSV (vesicular stomatitis virus), demonstrating remarkable potency and selectivity across various epigenetic and non-epigenetic targets.

Research Area

Cell Biology, Epigenetics & Chromatin, Infectious Disease & Virology

Key Properties

• CAS Number: 1255517-77-1
• MW: 527.74
• Formula: C₃₀H₄₉N₅O₃
• SMILES: O.N=1C=2C=C(OCCCN3CCCC3)C(OC)=CC2C(=NC1C4CCCCC4)NC5CCN(CC5)C(C)C
• Target: Influenza Virus,Histone Methyltransferase,Autophagy

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Influenza Virus,Histone Methyltransferase,Autophagy