UK 78282 hydrochloride

SKU: orb1703945

Description

UK 78282 hydrochloride is a potent and selective small molecule inhibitor of the Kv1.3 potassium channel. Its ability to suppress T cell activation makes it a valuable research tool for studying autoimmune diseases and T cell-mediated immune responses in both in vitro and in vivo experimental models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 136647-02-4
• MW: 466.05
• Purity: 99.89%
• Formula: C₂₉H₃₆ClNO₂
• SMILES: Cl.COc1ccc(CCCN2CCC(COC(c3ccccc3)c3ccccc3)CC2)cc1
• Target: Potassium Channel
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.29 mM);DMSO:50 mg/mL (107.28 mM);Ethanol:< 13.98 mg/mL

Bioactivity

• Target IC50:
  Kv1.3 channel:200 nM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Potassium Channel, PotassiumChannel, UK 78282 hydrochloride, UK 78282 Hydrochloride, UK78282 Hydrochloride, UK-78282 Hydrochloride, Kv1.3 channels

Compound Identifiers

PubChem CID

53393337