UIS4 Antibody

SKU: orb11636

Description

Goat polyclonal antibody to UIS4. UIS4 protein is expressed throughout liver stage development and localizes to the parasite vacuole (parasitophorous vacuole membrane).

Images & Validation

• Tested Applications: IF
• Dilution Range: IF:1:250-1:1,000
• Reactivity: Plasmodium
• Application Notes:
  The antibody solution should be gently mixed before use.

Key Properties

• Antibody Type: Primary Antibody
• Host: Goat
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: Antigen: Purified recombinant peptide produced in E. coli. Antigen Sequence: MNPEVREKFRIGKRIKEFDDVNTPQDISLINPVENPYPENSPENSPENSPEKYIEESHKHYTKRFLEQYTEPKPSDHTYSYSPTEEAYNTHYMASDTHEDYGKLFTDEHKDEINDNIVYHDELSDLVGEGNNVYNMENKSFGPYI
• Target: up-regulated in infective sporozoites gene 4
• Purification: Epitope affinity purified
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: PBS, 20% glycerol and 0.05% sodium azide
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Confocal immunofluorescence analysis of liver sections of a B6 mice infected with Plasmodium Berghei ANKA parasites using UIS4 antibody

Quick Database Links

Gene Symbol

up-regulated in infective sporozoites gene 4

LaMonte, Gregory M. et al. Dual RNA-seq identifies human mucosal immunity protein Mucin-13 as a hallmark of Plasmodium exoerythrocytic infection Nat Commun, 10, 488 (2019)

PubMed: 30700707

Favuzza, Paola et al. Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle Cell Host Microbe, 27, 642-658.e12 (2020)

PubMed: 32109369