Tubulin/HDAC-IN-4

SKU: orb3133881

Description

Tubulin/HDAC-IN-4 (compound 9n) is a dual inhibitor targeting microtubules (Tubulin) and HDAC, exhibiting IC50 values of 0.73, 0.43, 0.62, and 2.34 µM for HDAC1, HDAC2, HDAC6, and HDAC7, respectively. It disrupts microtubule assembly by binding to the colchicine site and induces apoptosis and G2/M cell cycle arrest. Additionally, Tubulin/HDAC-IN-4 significantly increases intracellular ROS levels and demonstrates both anti-angiogenic and anticancer properties.

Research Area

Cell Biology, Epigenetics & Chromatin, Epigenetics & Chromatin; Cell Biology, Immunology & Inflammation, Metabolism Research, Molecular Biology, Signal Transduction

Key Properties

• Formula: C₂₄H₂₆N₂O₆
• Target: Apoptosis,HDAC,Reactive Oxygen Species,Microtubule Associated

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis,HDAC,Reactive Oxygen Species,Microtubule Associated