Tubulin/HDAC-IN-1

SKU: orb1688511

Description

Tubulin/HDAC-IN-1 is a dual-action small molecule that inhibits tubulin polymerization and selectively targets HDAC8 (IC50 = 150 nM). It demonstrates potent anti-cancer activity in vitro by inducing G2/M phase arrest and apoptosis in various human cancer cell lines, making it a valuable tool for researching hematologic and solid tumors.

Research Area

Cell Biology, Epigenetics & Chromatin, Epigenetics & Chromatin; Cell Biology, Metabolism Research, Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 2413587-26-3
• MW: 374.39
• Formula: C₂₁H₁₈N₄O₃
• SMILES: N(C)(C=1C2=C(N=C(C#N)C1)C=CC=C2)C3=CC(/C=C/C(NO)=O)=C(OC)C=C3
• Target: Mitochondrial Metabolism,Others,Microtubule Associated,Apoptosis,HDAC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

146469200