Trityl candesartan

SKU: orb1962271

Description

Trityl candesartan is a key synthetic intermediate for the angiotensin II receptor blockers candesartan and candesartan cilexetil. It is utilized in pharmacological research for the in vitro and in vivo development and study of these antihypertensive agents.

Key Properties

• CAS Number: 139481-72-4
• MW: 682.77
• Purity: 99.33%
• Formula: C₄₃H₃₄N₆O₃
• SMILES: CCOC1=NC2=CC=CC(C(O)=O)=C2N1CC1=CC=C(C=C1)C1=C(C=CC=C1)C1=NN=NN1C(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1
• Target: Others
• Solubility: DMSO:50 mg/mL (73.23 mM)

Bioactivity

• In Vitro:
  Trityl candesartan behaves as a peroxyl radical scavenger. Furthermore, this higher antioxidant activity works in parallel with the improvement of the expansive activity over the angiotensin II-induced contracted human mesangial cells.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

10312563