Transcrocetinate disodium

SKU: orb1296259

Description

Transcrocetinate disodium, a saffron-derived compound, acts as a high-affinity NMDA receptor antagonist. This small molecule is utilized in neuroscience research, with studies investigating its potential neuroprotective effects in models of cerebral ischemia and excitotoxicity.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 591230-99-8
• MW: 372.37
• Purity: 99.22%
• Formula: C₂₀H₂₂Na₂O₄
• SMILES: O=C([O-])/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C([O-])=O.[Na+].[Na+]
• Target: iGluR,NMDAR
• Solubility: DMSO:Insoluble;H2O:4.42 mg/mL (11.87 mM)

Bioactivity

• In Vitro:
  Transcrocetinate has been shown to exert strong NMDA receptor affinity and is thought to be responsible for the CNS activity of saffron. Transcrocetinate at 10 μM level does not change viability while higher concentrations (40-160 μM) reduces significantly cellular viability.

Storage & Handling

• Storage: keep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Transcrocetinate, Transcrocetinate disodium, NMDA receptor, Ionotropic glutamate receptors, inhibit, Inhibitor, iGluR, Disodium trans-crocetinate

Compound Identifiers

PubChem CID

10287099