Trandolapril

SKU: orb1301883

Description

Trandolapril is an oral ACE inhibitor prodrug that is metabolized to its active form, trandolaprilat. It is widely used in cardiovascular research, including in vitro enzyme inhibition assays and in vivo models for studying hypertension and heart failure.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 87679-37-6
• MW: 430.54
• Purity: 99.83% (May vary between batches)
• Formula: C₂₄H₃₄N₂O₅
• SMILES: C([C@@H](N[C@@H](CCC1=CC=CC=C1)C(OCC)=O)C)(=O)N2[C@@]3([C@@](C[C@H]2C(O)=O)(CCCC3)[H])[H]
• Target: Angiotensin-converting Enzyme (ACE)
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.29 mM);DMSO:100 mg/mL (232.27 mM)

Storage & Handling

• Storage: keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

congestive heart failure, cellular fibronectin accumulation, collagen, CHF, ACE, arterial hypertrophy, Angiotensin-converting Enzyme, Angiotensin-converting Enzyme (ACE), Angiotensinconverting Enzyme (ACE), AngiotensinconvertingEnzyme, AngiotensinconvertingEnzyme(ACE), hypertension, Inhibitor, nonsulfhydryl, inhibit, myocardial infarction, orally active, spontaneously hypertensive rats, RU 44570, RU44570, RU-44570, UUD model, UUO model, unilateral ureteral obstruction, Trandolaprilat, Trandolapril

Compound Identifiers

PubChem CID

5484727